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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13450236bb3b8686be997e07f3f035e2b91d373df870d8dc72cd23c298860aa5' 
  AND token = 'vWsKr5Xw2ot98CiXuMSyCLp0ZnNkup8uYXYpr4O8XEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}