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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5334ea0762d960b9c157404f07eb2a83fbdc7363f4ea08df8f14ec3b8f5f5aee' 
  AND token = 'Al0/TyoBH6Pn0nMUZybo8jqfSIgjMq4Ss2T7J1fmHfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}