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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '607a3bbd7cad712e863850a7b50f49f20e65155ffdc9b2e4672b3d4b522b5294' 
  AND token = '3V7bbIyUHii/v8Wm588v2qVgwkYn244AvH0xXtDlnBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}