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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1be9b044454d1d6412a4fa213be4c1c22fd0ceeca4e3e81ae7b344b05fa1dd81' 
  AND token = 'NntEeCeH+isb7/IsxPp8REKo2KB+pw7snW1zQKVC2zY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}