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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0414ccd4dc1b1a48396be5db47f3b8c4825bf22f4369c211366cfa708ffbad1' 
  AND token = 'WeW7S2CrpeOJJZ2b0uqsdJN5m7N4+8k5fSdTUnm81f8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}