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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4510bf0edc8e04b39a80b61ea8af961475f8429ad0210f625931df844b488a4b' 
  AND token = 'M3iQhXQ+9x6g6+Dt4a0AwiPvNYHj+hpVYhi2pSe9Ya0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}