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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3682f49b7cd4afa90ca676e8e004efd93ba207aec736c53d3392ab5c60d361f' 
  AND token = 'pJ26wK82MGsw985y+WDkkWMWhrAi1YfkxXn0gh9S5/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}