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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18be75feeaca6554cae48c6ef775e0dbc25bd06af956b96ac56e5e509a1b4425' 
  AND token = 'nlgL/tBXN0M6qseLB/9EVvWWKeoCrGXg4PZI4yxTMVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}