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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fd2c1c938b50af34b2f2017a106a289772234f626e820a1876239eb7f30c06d' 
  AND token = 'eAL0mdLFPxT1HY93ZRdYLezOsBdJShocbQV54F1Ohmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}