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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffe486a97d345ee97a3f99f96ac79212002cf0ba1e95d396e2532c84a1bab3a0' 
  AND token = '2dSDwLWJNjeVLdcE5AneChhAqtb8+CviBitIvNEHCQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}