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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5912bf6ce6552561b518c20ac7dc50fc170d52bca338f010a155a0b8bfec944d' 
  AND token = 'SwtajZBKJiAyAGQ+3/2m2/x72RU4ZfE5dbph09AtiwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}