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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e536a0b3512094311f1c66aca05e6ecce5fbb109d227624572318ee05513ec57' 
  AND token = 'yHcG6LdsFAL9apPnJHSsR2yq2ya2ZuU8xd0ZnY66R1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}