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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca451d11f21eb411408941e7e4faa5d80b3ec3b1f8e9ec27cd2cdbba9ae957b3' 
  AND token = '4MBV1L/U/DGAqGRkx9DMQDcCAHoozo0WXiJbs/omgFY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}