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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3afb06e6e9ac3e16986e8f3e6f667ccf6d442e93b68b3bb6aad2e04f908ba914' 
  AND token = 'drjcTQGAxH7nsIXTAc1VnCAG5K4dDKiw6zoYeCDTcrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}