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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c4bb4c7f9329509e821a60f39628152b3ffd5110f38a81f775b09b43f9234f4' 
  AND token = '9456TW9iHfR3zJA0PmtDgPN44by0WutmNAhlWThJppM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}