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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48091941238f4a618444c3d4027aece88f873235f1f340c61cca219a6567a460' 
  AND token = 'nxi9vmOiF08Mufsooye5os2pHNKCU1G5lyJH2ccm0MU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}