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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44de6f274716b01637bbf4ce3924e1100b48bbc5ef0bba91680fe796bb768a7a' 
  AND token = 'aEvrPEN/OjXSEKM2C9fDGVMHBP56AYBooHMlZ1ta7NY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}