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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c59419f461a354234e7345b1d52048ef2c84557291bd305e31718aec4846a4c1' 
  AND token = 'eh8NVSO6G4t+rE/a5vuWSf5pCKggV/AKxj9mvO5mXjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}