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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2b1f6d110af6f6c8681aa6888e1dbde3a72f6e76752089fd53eb7c0e01b3f88' 
  AND token = '8QmEzFjtRrPquRyvF7b5FtgqURVh8RvwmcnJJvE2OHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}