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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '856bdbb92df1ef05ff47e84f63596a773084fb4fc3aaf4a034a738c0493e3e40' 
  AND token = 'n74dEJ2kYeDJk+3EEej83sn7Z59p5h8FR4ZdJ0z61PE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}