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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0224e35d6bd3c4d7f94e6aa6d3053894209ec7441a867058c4d1ca8e0f1574be' 
  AND token = 's1qogVKuY46KpXlPf91P7sd/zaj/ySgNlcSw6k95SkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}