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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5e83947f39096b52f5fa8a49dfac6faf0bc25833426bd01f6782d5130f30a40' 
  AND token = 'lpFFOc4kFNbwoF2mAL6+xsCjREU4Qlfqd52TKCmC6fk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}