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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e4cf1ace67f245f1cc5b69dc240cc1717239f177fb8ec19a106a2362d9ff41c' 
  AND token = 'UCdFYie4EnVPU1hTRphIUwMxG28Mk+dnPo/1Mu/u+bs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}