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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54e766db80c48666bd802dede672b69d35ac464531ef97fc4a85d8e61e928030' 
  AND token = 'v7MQqoJq5Gvet1MfDqxDCsQaGxIoc4RjB/PE5wnWtLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}