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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0282e118ad125ce4e01d74b3115e10d2ba0dca16d0cccc4784445c356d0c4696' 
  AND token = 'WFDEetH+Tt7T3NpXMbAoLzmSUUhzyzN4r54hVZz/XS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}