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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cbb2f6874857a96effc65f7b3b0810f55bd95ad2e8ddac9d982b18777d6935f' 
  AND token = '+sGe3JmwBfSrLJdkMS54YK3D7ZECwqxYMPQpfQDL2tc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}