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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc726079d6824649c4837d2db5d51f3aa05e8cf1b1e6a421a380aa5f071cb8e8' 
  AND token = 'Plq/qcngeJCJ3jkoNwr3a2kIZ0lW+48+wVoOZ3LS4As=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}