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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5e5285cdaf753e8cc9044cd856fd07ac03a9de433d4b6fb6dd0397bd91b61c8' 
  AND token = 'fkb+lql8MizOQIeI9hjySosuHyJXx78Xufpbar/Y5Zg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}