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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c43d6043c51d015dc703935c0f177ea3b02c5dc3ffa1d3a6a7238e006744e79c' 
  AND token = 'c5/R5APAr2VNUUezUorrnsD84HIKjokivoeMeAx98HM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}