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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f22519f6ded799fae1c7b0c6d1817d3916097d8c695369e9bd1aed769e1dde00' 
  AND token = 'tBCLXd+A+A5C+2sHITWdwkCNG760jA+UnLT0crfYyDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}