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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10f398ba6cdfb693c734c71704e750b50109c80aaa5b9dfab62a741a6fa6293e' 
  AND token = 'UFUxUoppHIHk394WEBwza3vagN4wbB4UEM4u3e6c0gw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}