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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9e1fd904a224dde4be12ecfb51768b77e86507efafbd3a75acabc7309f50fe5' 
  AND token = 'QS/+dEvdE1XV9sX5hEZ2642FLqiUHJjC2ZfHO+qT52Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}