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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef3a52e047a304311c3cc3e64c5f6b9e862b855435cced04f02a31e4f36c64d2' 
  AND token = 'TQpTNX9DDknlY7laDan0fszGY1Z+2esIb04Wu6qi+xQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}