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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dbe1c660c7e2343d36e4018bd8e3a0e27dae15f0f62dfc7522816f16ed49131' 
  AND token = 'UKeoFgY0vSae7WHv8gZ9eWmHlzUu4OO+TnfF+v/kKX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}