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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ba7c97107cc49b5f20554d2cabfa16e83669289d5780d00ab2a9ae66bda2bb4' 
  AND token = 'tjB0oHRdF0Z9zlou1mRGFQiamZYUYkmTQkQS33/iVhY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}