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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '516a37593d387e3a5f9864c4f992ed717cd2ccfa200722fc9005408755d27313' 
  AND token = 'op6khG+qA/awS4ff+lVPXsv5c+su2Rb8WC5yCM3YXRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}