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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44d34b844ea1e80b998c59b3abd552105c8f7b15f91d16c33c89de3f8de55662' 
  AND token = '2KXANpI6x/AuiyK8olP+1TpsEKd3meuZ1g8rgFMrU7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}