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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8aebd5dc3e618eca524c79a2e5d3c099e2419c7c849733bad59cb6be3f6c27d' 
  AND token = 'roi3wQawQHjcVm3gIt6pVCkl+KwsXuz36gXTNB8JEEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}