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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b7d71ec7fd7eed92b9fd186df691c994515bc47c77323207cc90fc4e5777d20' 
  AND token = 'VxErRueoAIhpa8VcAylQnbp/aoEHwrhuj+z3Z61Bn9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}