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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2969a60274badf8aa1a85f3ae60534df35f28564bb5127a1a1f53b3cb6909aee' 
  AND token = '8uzt69t8W01fub1tned3togXClEDp45vI47Lhcjkrxk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}