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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75f3169c935ca79d477f66666fba0d176bc26ea7ad76b95b0718f613e56ccf89' 
  AND token = 'Lr9Qx/pHy/qeOF+LVOFVh9FbvSPj6UNe7FvODi7xO5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}