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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8239d1119f1b0d5d166352dc9134feaec9c50d93fd57c11fa302da7adc05a64' 
  AND token = 'z+8QBhwhUnqEjPb5PxSWwXXPr4R3/5hgQ3OXktbI5Aw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}