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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3151c81185e3083517e545e2ffc9e45346e29cb783f1c7565a7d13f10477306b' 
  AND token = 'tJGE6OUtSsMiJ36rGxflgsAL0JHQu5WdpsoVwUaJ0L0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}