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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6c186b02c35b911e22102ead531921afef0144202fac261cfa07ca2510adf4d' 
  AND token = 'f/ZaR5JwbdWs3A2DRT2IPGu2o0ulU2Uecs6LElq4ZCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}