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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4526b46756e80306410194f14a629eb3f915f393f1b4d54325a2a5b3773fdd90' 
  AND token = 'f0ktmx9Xr4HYeD2WKHcz003AAKL/p6oynA33Rggpypk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}