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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4709ac49c1756eea4732c25f4e8c14ccc69c9e69baf24f0b3bc8d443fa98001a' 
  AND token = 'yt/I5zcXzt3Koswh7V+l1+YSos08+laWlZ8ZNyW2F2w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}