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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ce194c01a37fa489c6a12f4bc1ce50637157b7abf0a67d24910b1f317c9e2e1' 
  AND token = '0Wti7YhcGdMfJJrN5v7gf43l01tjQULqLoAz+1WotkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}