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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21e2504b0dea21ec9154d9d4fdd43aa92f1df812bd85cd4edb394c0e6e129de3' 
  AND token = 'r7vh5ChH5q9Olxfp/6IyJq9gE5sQtPC+dynYp+Bo/ws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}