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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1e51ea0b4a1786833f63b39373cd51a1bc707f79ca814a8e779545d6c8a0352' 
  AND token = 'ntgSap7Jl1co2p1XShXkYNdkxY63KIbLkasSIHXFJnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}