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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c215090cfb2a10e4dad9b8f0dfd246199a8ed3299b7daf78ef00afa65220448' 
  AND token = 'TEZITX5yLz+UlVCSs4+yxgmuwQy97Ex9PM2UFIwO8QA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}